Brent R. Stockwell


On his book The Quest for the Cure: The Science and Stories Behind the Next Generation of Medicines

Cover Interview of July 25, 2011

Editor’s note

Originally, this interview ran on the Rorotoko cover page under the headline

“The future of medicine is balanced on the fulcrum of the undruggable proteins.”

We highlighted two quotes.

On the first page:

“The majority of proteins are considered undruggable.  These proteins control nearly every disease process, from many types of cancer to neurodegenerative diseases such as Alzheimer’s, Parkinson’s and Lou Gehrig’s, to many other diseases.”

On the second:

“Many of the root causes of diseases are considered undruggable and cannot be addressed directly with medicines. If we could solve the mystery of protein druggability, we could open up a vast number of possibilities for new medicines, and ultimately end the drug discovery crisis.”